The Merbl Lab


Open positions

We are searching for ambitious and dedicated candidates who are self-driven, highly motivated and able to work independently as well as part of a team. We combine cutting–edge technologies in immunoproteomics, biochemical immunology, cell biology and genomics to address fundamental as well as transnational questions related to proteostasis control of cancer and immune regulation.


Project I: Golgi Apparatus-Related degradation

We are looking for a cell biologist to study the role of the ubiquitin-proteasome system in the maintenance and organization of the Golgi apparatus and elucidating novel regulation of the newly identified Golgi stress response. The project will involve cell and molecular biological approaches, complemented by mouse genetic models. Experience in CRISPR and microscopy techniques is advantageous. Applicants should have a PhD in biology, biochemistry, cell biology or a related subject.


Project II: E3 ligases in immune signaling

We are looking for a structural biologist (ideally with some electron microscopy experience) to study novel enzymes regulating immune signaling. The project will be centered on a structural biology approach to study Ub ligase complexes.


Projects III+IV: Cancer vaccines and sensitizing response to immunotherapy

We are looking for an MD or PhD to utilize our novel immune-proteomics approaches to design novel treatments for cancer therapy. Knowledge and experience in immunology/cancer biology and experience with in vivo models is advantageous. Applicants should have a PhD in immunology, cancer biology or a related subject. MD scientists with a keen interest in life science research are also welcome to apply.


Informal inquiries can be directed to

Formal applications, including a CV, the names and contact details of three referees and a concise description of research interests and future plans should be addressed to: